Triple antiplatelet therapy during percutaneous coronary intervention is associated withimproved outcomes including one-year survival

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Triple antiplatelet therapy during percutaneous coronary intervention is associated with improved outcomes including one-year survival: results from the Do Tirofiban and ReoProGive Similar Efficacy Outcome Trial (TARGET).

OBJECTIVE We sought to examine if clopidogrel treatment initiated before coronary stenting improved clinical outcomes among patients receiving aspirin and a glycoprotein (GP) IIb/IIIa inhibitor. BACKGROUND Antiplatelet therapy plays a pivotal role in contemporary percutaneous coronary interventions (PCI). METHODS Outcomes among 4,809 patients randomized to tirofiban or abciximab during PCI ...

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Dual Antiplatelet Therapy in Percutaneous Coronary Intervention

In 2016, dual antiplatelet therapy (DAPT) assumes its 20th anniversary since the publication of the first randomized clinical trial establishing the superiority of DAPT over anticoagulant therapy among patients undergoing percutaneous coronary intervention (PCI) (Figure). Because then, both antiplatelet therapy and PCI have undergone continued refinement. Clopidogrel substituted ticlopidine, an...

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Dual Antiplatelet Therapy in Percutaneous Coronary Intervention

In 2016, dual antiplatelet therapy (DAPT) assumes its 20th anniversary since the publication of the first randomized clinical trial establishing the superiority of DAPT over anticoagulant therapy among patients undergoing percutaneous coronary intervention (PCI) (Figure). Because then, both antiplatelet therapy and PCI have undergone continued refinement. Clopidogrel substituted ticlopidine, an...

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Triple versus Dual Antiplatelet Therapy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

growth factor (VEGF) levels myocardial perfusion images and cardiac function, as well as the possible mechanisms to improve myocardial perfusion. Methods Total 102 cases were selected, 5 patients were lost. Finally 97 patients included, 77 males and 20 females, aged 56613. Of whom, 30 cases suffered from acute myocardial infarction (AMI), 48 from acute coronary syndromes (ACS), and 19 from chro...

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Antiplatelet and anticoagulant therapy in elective percutaneous coronary intervention

Thrombosis plays a major role in acute vessel closure both after coronary balloon angioplasty and after stenting. This review will address the role of antiplatelet and anticoagulant therapy in preventing early thrombotic complications after percutaneous coronary intervention. The focus will be on agents that are routinely available and commonly used.

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2003

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(03)00944-6